6050-48-2
Chemical Structure
Cholyl-CoA
Synonym(s): Cholyl-coenzyme A
- CAS No.: 6050-48-2
- Formula:C45H74N7O20P3S
- Molecular Weight:1158.09
InChIKey: ZKWNOTQHFKYUNU-JGCIYWTLSA-N
SMILES: C[C@@H]([C@H]1CC[C@@H]2[C@]1(C)[C@@H](O)C[C@H]3[C@H]2[C@H](O)C[C@H]4[C@]3(C)CC[C@@H](O)C4)CCC(SCCNC(CCNC([C@H](O)C(C)(COP(O)(OP(O)(OC[C@H]5O[C@@H](N6C=NC7=C(N)N=CN=C76)[C@H](O)[C@@H]5OP(O)(O)=O)=O)=O)C)=O)=O)=O
Biological Activity: Cholyl-CoA (Cholyl-coenzyme A) is a biologically active steroidal acyl-coenzyme A intermediate. Cholyl-CoA reacts with taurine in the presence of liver supernatant enzymes to promote the synthesis of taurocholic acid. Cholyl-CoA is formed by the activation of cholic acid with coenzyme A. Cholyl-CoA plays a key role in the biosynthesis, metabolism and conjugation reactions of bile acids[1].
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Cholyl-CoA | Cholyl-CoA (Cholyl-coenzyme A) is a biologically active steroidal acyl-coenzyme A intermediate. Cholyl-CoA reacts with taurine in the presence of liver supernatant enzymes to promote the synthesis of taurocholic acid. Cholyl-CoA is formed by the activation of cholic acid with coenzyme A. Cholyl-CoA plays a key role in the biosynthesis, metabolism and conjugation reactions of bile acids. | |||||||||||||||||||||
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Keywords
