60569-19-9
60569-19-9
Chemical Structure
Propiverine
- CAS 番号: 60569-19-9
- Formula:C23H29NO3
- Molecular Weight:367.48
IUPAC Name: 1-methylpiperidin-4-yl 2,2-diphenyl-2-propoxyacetate
InChIKey: QPCVHQBVMYCJOM-UHFFFAOYSA-N
SMILES: O=C(C(C1=CC=CC=C1)(C2=CC=CC=C2)OCCC)OC3CCN(CC3)C
Biological Activity: Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research[1][2].
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Propiverine | Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research. | |||||||||||||||||||||
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References
- [1]. McKeage K. Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms. Clin Drug Investig. 2013 Jan;33(1):71-91. [Content Brief]
- [2]. Madersbacher H, Mürtz G. Efficacy, tolerability and safety profile of propiverine in the treatment of the overactive bladder (non-neurogenic and neurogenic). World J Urol. 2001 Nov;19(5):324-35. [Content Brief]
Keywords
