612527-56-7
Chemical Structure
HZ166
- CAS No.: 612527-56-7
- Formula:C21H16N4O2
- Molecular Weight:356.38
IUPAC Name: ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate
InChIKey: ZSEDMNMFODMQRD-UHFFFAOYSA-N
SMILES: O=C(OCC)C1=C2N(C3=CC=C(C=C3C(C4=NC=CC=C4)=NC2)C#C)C=N1
Biological Activity: HZ166 is a GABAA receptor subtype-selective benzodiazepine site agonist with preferential activity at α2- and α3-GABAA receptors. HZ166 shows anti-hyperalgesic effects[1]. HZ166 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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HZ166 | HZ166 is a GABAA receptor subtype-selective benzodiazepine site agonist with preferential activity at α2- and α3-GABAA receptors. HZ166 shows anti-hyperalgesic effects. HZ166 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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Keywords
