61263-32-9
Chemical Structure
9-deoxy-9-methylene Prostaglandin E2
Synonym(s): 9-Deoxy-9-methylene PGE2
- CAS No.: 61263-32-9
- Formula:C21H34O4
- Molecular Weight:350.49
IUPAC Name: (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-methylenecyclopentyl)hept-5-enoic acid
InChIKey: VKEJXDXJUFQESA-DLMPNJEASA-N
SMILES: O[C@H]1[C@@H]([C@H](C(C1)=C)C/C=C\CCCC(O)=O)/C=C/[C@H](CCCCC)O
Biological Activity: 9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2. 9-deoxy-9-methylene PGE2 retains the biological profile of PGE2 with fewer side effects. In the rat 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in decreasing blood pressure. It also stimulates the gerbil colon and primate uterus at the same potency as PGE2.
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9-deoxy-9-methylene Prostaglandin E2 | 9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2. 9-deoxy-9-methylene PGE2 retains the biological profile of PGE2 with fewer side effects. In the rat 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in decreasing blood pressure. It also stimulates the gerbil colon and primate uterus at the same potency as PGE2. | |||||||||||||||||||||
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Keywords
