61318-91-0
61318-91-0
Chemical Structure
Sulconazole mononitrate
Synonym(s): (±)-Sulconazole mononitrate
- CAS No.: 61318-91-0
- Formula:C18H16Cl3N3O3S
- Molecular Weight:460.76
IUPAC Name: 1-(2-((4-chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate
InChIKey: CRKGMGQUHDNAPB-UHFFFAOYSA-N
SMILES: [O-][N+](O)=O.ClC1=CC=C(C(SCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=C1
Biological Activity: Sulconazole mononitrate ((±)-Sulconazole mononitrate), an imidazole derivative, is a broad-spectrum fungicide. Sulconazole mononitrate can be used for the research of dermatomycoses, pityriasis versicolor, and cutaneous candidiasis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sulconazole mononitrate | 99.96% | Sulconazole mononitrate ((±)-Sulconazole mononitrate), an imidazole derivative, is a broad-spectrum fungicide. Sulconazole mononitrate can be used for the research of dermatomycoses, pityriasis versicolor, and cutaneous candidiasis. | ||||||||||||||||||||
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Sulconazole mononitrate (Standard) | ≥98% | Sulconazole (mononitrate) (Standard) is the analytical standard of Sulconazole (mononitrate). This product is intended for research and analytical applications. Sulconazole mononitrate ((±)-Sulconazole mononitrate), an imidazole derivative, is a broad-spectrum fungicide. Sulconazole mononitrate can be used for the research of dermatomycoses, pityriasis versicolor, and cutaneous candidiasis. | ||||||||||||||||||||
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Antifungal agent 53 | Antifungal agent 53 (A03) is a potent inhibitor of Candida albicans CYP51 with antifungal activity. Antifungal agent 53 prevents the formation of fungi biofilms. Antifungal agent 53 also exhibits good safety. | |||||||||||||||||||||
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Dapaconazole | 99.76% | Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM. | ||||||||||||||||||||
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Butoconazole nitrate (Standard) | ≥98% | Butoconazole (nitrate) (Standard) is the analytical standard of Butoconazole (nitrate). This product is intended for research and analytical applications. Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis. | ||||||||||||||||||||
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Fenticonazole Nitrate (Standard) | ≥98% | Fenticonazole (Nitrate) (Standard) is the analytical standard of Fenticonazole (Nitrate). This product is intended for research and analytical applications. Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis. | ||||||||||||||||||||
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Econazole nitrate | 98.0% | Econazole nitrate is an imidazole class antifungal medication. Econazole nitrate also has antibacterial activity. | ||||||||||||||||||||
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Miconazole (Standard) | 99.80% | Miconazole (Standard) is the analytical standard of Miconazole. This product is intended for research and analytical applications. Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects. | ||||||||||||||||||||
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Econazole | 99.93% | Econazole ((±)-Econazol) is an orally active imidazole antifungal agent, as well as a cytochrome P-450 inhibitor and a blocker of calcium and manganese ion uptake. Econazole is active against a variety of fungi and some Gram-positive bacteria, but has no significant activity against Gram-negative bacteria. Econazole can inhibit the synthesis of prostaglandins and can also induce liver damage. | ||||||||||||||||||||
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Isoconazole nitrate | 98.0% | Isoconazole nitrate is a broad-spectrum antimicrobial agent with a highly effective antimycotic and gram-positive antibacterial activity, exhibiting a rapid rate of absorption and low systemic exposure potential. | ||||||||||||||||||||
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Sulconazole | Sulconazole is a potent antifungal agent in the imidazole class. Sulconazole blocks the NF-κB/IL-8 signaling pathway and CSC (Cancer stem cells) formation. Sulconazole inhibits tumor growth, and can be used for breast cancer research. | |||||||||||||||||||||
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References
- [1]. P Benfield, et al. Sulconazole. A review of its antimicrobial activity and therapeutic use in superficial dermatomycoses. Drugs. 1988 Feb;35(2):143-53. [Content Brief]
- [2]. R A Fromtling. Overview of medically important antifungal azole derivatives. Clin Microbiol Rev. 1988 Apr; 1(2): 187–217. [Content Brief]
