6146-52-7
6146-52-7
Chemical Structure
5-Nitroindole
- CAS. Nr.: 6146-52-7
- Formula:C8H6N2O2
- Molecular Weight:162.15
IUPAC Name: 5-nitro-1H-indole
InChIKey: OZFPSOBLQZPIAV-UHFFFAOYSA-N
SMILES: O=[N+]([O-])C1=CC2=C(NC=C2)C=C1
Biological Activity: 5-Nitroindole is a mutagenic nitroarene and universal base analog. 5-Nitroindole significantly reduces the cellular adenylate energy charge by decreasing ATP levels and increasing AMP levels. 5-Nitroindole inhibits lipid peroxidation[1][2].
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5-Nitroindole | 98.58% | 5-Nitroindole is a mutagenic nitroarene and universal base analog. 5-Nitroindole significantly reduces the cellular adenylate energy charge by decreasing ATP levels and increasing AMP levels. 5-Nitroindole inhibits lipid peroxidation. | ||||||||||||||||||||
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References
- [1]. Dubin M, et al. Effect of 5-nitroindole on adenylate energy charge, oxidative phosphorylation, and lipid peroxidation in rat hepatocytes. Biochem Pharmacol. 1994 Oct 7;48(7):1483-92. [Content Brief]
- [2]. Loakes D, et al. 5-Nitroindole as an universal base analogue. Nucleic Acids Res. 1994 Oct 11;22(20):4039-43. [Content Brief]
Keywords
