617690-98-9
617690-98-9
Chemical Structure
SK-7041
- CAS No.: 617690-98-9
- Formula:C19H21N3O3
- Molecular Weight:339.39
IUPAC Name: (E)-4-(dimethylamino)-N-(4-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzyl)benzamide
InChIKey: WWMASNYTEATYTC-KPKJPENVSA-N
SMILES: ONC(/C=C/C(C=C1)=CC=C1CNC(C2=CC=C(C=C2)N(C)C)=O)=O
Biological Activity: SK-7041 is a HDAC inhibitor with the IC50 of 172 nM. SK-7041 induces the hyperacetylation of histones H3 and H4 .SK-7041 inhibits tumor cell growth in vivo and in vitro, induces cell apoptosis, and arrests cell cycle at the G1 phase[1].
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SK-7041 | SK-7041 is a HDAC inhibitor with the IC50 of 172 nM. SK-7041 induces the hyperacetylation of histones H3 and H4 .SK-7041 inhibits tumor cell growth in vivo and in vitro, induces cell apoptosis, and arrests cell cycle at the G1 phase. | |||||||||||||||||||||
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