625114-41-2
Chemical Structure
Piragliatin
Synonym(s): RO4389620
- CAS No.: 625114-41-2
- Formula:C19H20ClN3O4S
- Molecular Weight:421.90
IUPAC Name: (R)-2-(3-chloro-4-(methylsulfonyl)phenyl)-3-((R)-3-oxocyclopentyl)-N-(pyrazin-2-yl)propanamide
InChIKey: XEANIURBPHCHMG-SWLSCSKDSA-N
SMILES: O=C(NC1=NC=CN=C1)[C@@H](C2=CC=C(S(=O)(C)=O)C(Cl)=C2)C[C@@H]3CC(CC3)=O
Biological Activity: Piragliatin (RO4389620) is an activator for glucokinase, which reduces endogenous glucose production, increases β-cell function and glucose utilization, and thus decreases the blood glucose levels. Piragliatin exhibits antidiabetic efficacy[1].
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Piragliatin | Piragliatin (RO4389620) is an activator for glucokinase, which reduces endogenous glucose production, increases β-cell function and glucose utilization, and thus decreases the blood glucose levels. Piragliatin exhibits antidiabetic efficacy. | |||||||||||||||||||||
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Keywords