63250-36-2
63250-36-2
Chemical Structure
Epicaptopril
Synonym(s): SQ 14534
- CAS No.: 63250-36-2
- Formula:C9H15NO3S
- Molecular Weight:217.29
IUPAC Name: ((R)-3-mercapto-2-methylpropanoyl)-L-proline
InChIKey: FAKRSMQSSFJEIM-BQBZGAKWSA-N
SMILES: SC[C@H](C)C(N1[C@@H](CCC1)C(O)=O)=O
Biological Activity: Epicaptopril (SQ 14534) is the derivative of Captopril (HY-B0368). Epicaptopril is an inhibitor for angiotensin-converting enzyme (ACE). Epicaptopril enhances vasodilation in an endothelium-derived relaxing factor (EDRF)-dependent manner. Epicaptopril is a free radical scavenger, and can be used in research about oxidative stress and free radical damage caused cardiovascular disorders[1][2].
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Epicaptopril | Epicaptopril (SQ 14534) is the derivative of Captopril (HY-B0368). Epicaptopril is an inhibitor for angiotensin-converting enzyme (ACE). Epicaptopril enhances vasodilation in an endothelium-derived relaxing factor (EDRF)-dependent manner. Epicaptopril is a free radical scavenger, and can be used in research about oxidative stress and free radical damage caused cardiovascular disorders. | |||||||||||||||||||||
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References
- [1]. Chopra M, et al., Free radical scavenging: a potentially beneficial action of thiol-containing angiotensin converting enzyme inhibitors. Biochem Soc Trans. 1990 Dec;18(6):1184-5. [Content Brief]
- [2]. Shultz PJ, et al., Effects of antihypertensive agents on endothelium-dependent and endothelium-independent relaxations. Br J Clin Pharmacol. 1989;28 Suppl 2(Suppl 2):151S-157S. [Content Brief]
