64625-55-4
64625-55-4
Chemical Structure
19(R)-Hydroxy prostaglandin E1
Synonym(s): 19(R)-Hydroxy PGE1
- CAS No.: 64625-55-4
- Formula:C20H34O6
- Molecular Weight:370.48
IUPAC Name: 7-((1R,2R,3R)-2-((3S,7R,E)-3,7-dihydroxyoct-1-en-1-yl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid
InChIKey: QVVXWHIDRKRPMO-VOSXNNSYSA-N
SMILES: OC(CCCCCC[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@@H](O)CCC[C@H](O)C)=O
Biological Activity: 19(R)-Hydroxy prostaglandin E1 (19(R)-Hydroxy PGE1), the major prostaglandin in primate semen, is an agonist of EP1 and EP3 receptor subtypes and exhibits contractile activity on smooth muscle preparations[1][2].
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19(R)-Hydroxy prostaglandin E1 | 19(R)-Hydroxy prostaglandin E1 (19(R)-Hydroxy PGE1), the major prostaglandin in primate semen, is an agonist of EP1 and EP3 receptor subtypes and exhibits contractile activity on smooth muscle preparations. | |||||||||||||||||||||
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References
- [1]. Kelly RW, et al. 19-Hydroxyprostaglandin E1 as a major component of the semen of primates. Nature. 1976 Apr 8;260(5551):544-5. [Content Brief]
- [2]. Woodward DF, et al. Identification of 19 (R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist. Prostaglandins. 1993 Oct;46(4):371-83. [Content Brief]
