65222-35-7
65222-35-7
Chemical Structure
Pazelliptine
Synonym(s): Pazellipticine; BD-40
- CAS No.: 65222-35-7
- Formula:C22H27N5
- Molecular Weight:361.48
IUPAC Name: N1,N1-diethyl-N3-(6-methyl-5H-pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolin-10-yl)propane-1,3-diamine
InChIKey: LPHSYQSMAGVYNT-UHFFFAOYSA-N
SMILES: CCN(CC)CCCNC1=NC=CC2=C1C=C3C4=CN=CC=C4NC3=C2C
Biological Activity: Pazelliptine (Pazellipticine) is a DNA topoisomerase inhibitor and antitumour agent[1][2].
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Pazelliptine | Pazelliptine (Pazellipticine) is a DNA topoisomerase inhibitor and antitumour agent. | |||||||||||||||||||||
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References
- [1]. Balosso J, et al. Additive and supraadditive interaction between ionizing radiation and pazelliptine, a DNA topoisomerase inhibitor, in Chinese hamster V-79 fibroblasts. Cancer Res. 1991 Jun 15;51(12):3204-11. [Content Brief]
- [2]. Fontaine-Aupart M P, et al. Proton and charge transfer in the intercalating antitumour drug pazelliptine. Journal of the Chemical Society, Perkin Transactions 2, 1996 (8): 1767-1774.
