65236-62-6
65236-62-6
Chemical Structure
Dehydrocrenatidine
Synonym(s): Kumujian G; O-Methylpicrasidine I
- CAS No.: 65236-62-6
- Formula:C15H14N2O2
- Molecular Weight:254.28
IUPAC Name: 4,8-dimethoxy-1-vinyl-9H-pyrido[3,4-b]indole
InChIKey: LDWBTKDUAXOZRB-UHFFFAOYSA-N
SMILES: COC1=CC=CC2=C1NC3=C2C(OC)=CN=C3C=C
Biological Activity:
Dehydrocrenatidine, a natural alkaloid, is a specific JAK inhibitor. Dehydrocrenatidine inhibits voltage-gated sodium channels and ameliorates mechanic allodia in a rat model of neuropathic pain[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dehydrocrenatidine | 98.0% | Dehydrocrenatidine, a natural alkaloid, is a specific JAK inhibitor. Dehydrocrenatidine inhibits voltage-gated sodium channels and ameliorates mechanic allodia in a rat model of neuropathic pain. |
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References
- [1]. Jing Zhang, et al. Dehydrocrenatidine is a novel janus kinase inhibitor. Mol Pharmacol. 2015 Apr;87(4):572-81. [Content Brief]
- [2]. Fang Zhao, et al. Dehydrocrenatidine Inhibits Voltage-Gated Sodium Channels and Ameliorates Mechanic Allodia in a Rat Model of Neuropathic Pain. Toxins (Basel). 2019 Apr 18;11(4):229. [Content Brief]
