65860-38-0
65860-38-0
Chemical Structure
AA 497
- CAS No.: 65860-38-0
- Formula:C14H22ClNO3
- Molecular Weight:287.78
IUPAC Name: (1S,2S)-5-(hydroxymethyl)-2-(isopropylamino)-1,2,3,4-tetrahydronaphthalene-1,6-diol hydrochloride
InChIKey: GUXIVSFTPDBQRU-KYSPHBLOSA-N
SMILES: OCC1=C2C([C@@H]([C@H](CC2)NC(C)C)O)=CC=C1O.Cl
Biological Activity: AA 497 is an adrenergic beta-2 agonist. AA 497 is a bronchodilator[1][2].
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AA 497 | AA 497 is an adrenergic beta-2 agonist. AA 497 is a bronchodilator. | |||||||||||||||||||||
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References
- [1]. Inatomi N, et al. Pharmacological studies of trans-6-hydroxy-5-hydroxymethyl-2-isopropylamino-1,2,3,4,-tetrahydro-1-naphthalenol hydrochloride (AA-497), a new potent bronchodilator. Arzneimittelforschung. 1980;30(2):276-85. [Content Brief]
- [2]. Kimura I, et al. Difference between adrenergic beta 1- and beta 2-blocking effects on isoproterenol-induced Ca spike suppression in guinea-pig taenia coli. Jpn J Pharmacol. 1983 Dec;33(6):1271-8. [Content Brief]
