66648-35-9
Chemical Structure
Z-Gly-Pro-Arg-pNA
Synonym(s): CBZ-Chromozym TH
- CAS No.: 66648-35-9
- Formula:C27H34N8O7
- Molecular Weight:582.61
IUPAC Name: benzyl (2-((S)-2-(((S)-1-amino-5-guanidino-1-oxopentan-2-yl)(4-nitrophenyl)carbamoyl)pyrrolidin-1-yl)-2-oxoethyl)carbamate
InChIKey: NOMBSNGDLFJFII-VXKWHMMOSA-N
SMILES: N=C(N)NCCC[C@@H](C(N)=O)N(C([C@H]1N(C(CNC(OCC2=CC=CC=C2)=O)=O)CCC1)=O)C3=CC=C([N+]([O-])=O)C=C3
Biological Activity: Z-Gly-Pro-Arg-pNA (z-GPR-pNA) is a photometric substrate in Prostate-Specific Antigen (PSA) activation protease assays. Z-Gly-Pro-Arg-pNA (z-GPR-pNA) can be used for the test of trypsin activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Z-Gly-Pro-Arg-pNA | 98.47% | Z-Gly-Pro-Arg-pNA (z-GPR-pNA) is a photometric substrate in Prostate-Specific Antigen (PSA) activation protease assays. Z-Gly-Pro-Arg-pNA (z-GPR-pNA) can be used for the test of trypsin activity. | ||||||||||||||||||||
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- [1]. Oliver C Rogers, et al. PSA-selective activation of cytotoxic human serine proteases within the tumor microenvironment as a therapeutic strategy to target prostate cancer. Oncotarget. 2018 Apr 27;9(32):22436-22450. [Content Brief]
- [2]. Teaster T Baird Jr, et al. Conversion of trypsin to a functional threonine protease. Protein Sci. 2006 Jun;15(6):1229-38. [Content Brief]
Keywords
