6698-26-6
6698-26-6
Chemical Structure
2',5'-Dideoxyadenosine
- CAS No.: 6698-26-6
- Formula:C10H13N5O2
- Molecular Weight:235.24
IUPAC Name: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-methyltetrahydrofuran-3-ol
InChIKey: FFHPXOJTVQDVMO-DSYKOEDSSA-N
SMILES: C[C@@H]1[C@H](C[C@H](N2C=NC3=C(N=CN=C32)N)O1)O
Biological Activity: 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart[1][2].
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2',5'-Dideoxyadenosine | 99.86% | 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart. | ||||||||||||||||||||
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2',5'-Dideoxyadenosine (Standard) | ≥98% | 2',5'-Dideoxyadenosine (Standard) is the analytical standard of 2',5'-Dideoxyadenosine. This product is intended for research and analytical applications. 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart. | ||||||||||||||||||||
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References
- [1]. Bushfield M, et al. Tissue levels, source, and regulation of 3'-AMP: an intracellular inhibitor of adenylyl cyclases. Mol Pharmacol. 1990 Dec;38(6):848-53. [Content Brief]
- [2]. Hartmann M, et al. Isoproterenol antagonistic effect of 2',5'-dideoxyadenosine in the isolated perfused guinea-pig heart. J Mol Cell Cardiol. 1993 Mar;25(3):331-8. [Content Brief]
