6713-27-5
Chemical Structure
Moronic acid
Synonym(s): (+)-Moronic acid
- CAS No.: 6713-27-5
- Formula:C30H46O3
- Molecular Weight:454.68
IUPAC Name: (4aS,6aR,6bR,8aR,12aR,12bR,14aS)-2,2,6a,6b,9,9,12a-heptamethyl-10-oxo-3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14a-octadecahydropicene-4a(2H)-carboxylic acid
InChIKey: UMYJVVZWBKIXQQ-QALSDZMNSA-N
SMILES: C[C@]12[C@]3([C@@](CC[C@]1([H])[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC2)C)([H])C5=CC(C)(C)CC[C@@]5(CC3)C(O)=O)C
Biological Activity: Moronic Acid is a triterpenoid compound, which is an orally available anti-HIV agent with anti-inflammatory activity. Moronic Acid can inhibit viral replication, with an EC50 value of <1 μg/mL. Moronic Acid can be isolated from Brazilian propolis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Moronic acid | 98.6% | Moronic Acid is a triterpenoid compound, which is an orally available anti-HIV agent with anti-inflammatory activity. Moronic Acid can inhibit viral replication, with an EC50 value of <1 μg/mL. Moronic Acid can be isolated from Brazilian propolis. | ||||||||||||||||||||
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References
- [1]. Ito J, et al. Anti-AIDS agents. 48.(1) Anti-HIV activity of moronic acid derivatives and the new melliferone-related triterpenoid isolated from Brazilian propolis. J Nat Prod. 2001 Oct;64(10):1278-81. [Content Brief]
- [2]. Shuiliang Ruan, et al. Moronic acid improves intestinal inflammation in mice with chronic colitis by inhibiting intestinal macrophage polarization. J Biochem Mol Toxicol. 2022 Nov;36(11):e23188. [Content Brief]
- [3]. M Kurokawa, et al. Anti-herpes simplex virus activity of moronic acid purified from Rhus javanica in vitro and in vivo. J Pharmacol Exp Ther. 1999 Apr;289(1):72-8. [Content Brief]
