67881-98-5
Chemical Structure
2-Methacryloyloxyethyl phosphorylcholine
- CAS No.: 67881-98-5
- Formula:C11H22NO6P
- Molecular Weight:295.27
IUPAC Name: 2-(methacryloyloxy)ethyl (2-(trimethylammonio)ethyl) phosphate
InChIKey: ZSZRUEAFVQITHH-UHFFFAOYSA-N
SMILES: C=C(C)C(OCCOP(OCC[N+](C)(C)C)([O-])=O)=O
Biological Activity: 2-Methacryloyloxyethyl phosphorylcholine is a polymer monomer containing a phospholipid polar group. 2-Methacryloyloxyethyl phosphorylcholine polymers modify the surface properties of materials and reduce protein-surface interactions, reduce IL-8 production, inhibit cell, Staphylococcus aureus, and Porphyromonas gingivalis adhesion. 2-Methacryloyloxyethyl phosphorylcholine is used in the study of medical device-associated infections, periodontitis, and dental caries[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Methacryloyloxyethyl phosphorylcholine | 99.68% | 2-Methacryloyloxyethyl phosphorylcholine is a polymer monomer containing a phospholipid polar group. 2-Methacryloyloxyethyl phosphorylcholine polymers modify the surface properties of materials and reduce protein-surface interactions, reduce IL-8 production, inhibit cell, Staphylococcus aureus, and Porphyromonas gingivalis adhesion. 2-Methacryloyloxyethyl phosphorylcholine is used in the study of medical device-associated infections, periodontitis, and dental caries. | ||||||||||||||||||||
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References
- [1]. Ishihara K, et al. Inhibition of fibroblast cell adhesion on substrate by coating with 2-methacryloyloxyethyl phosphorylcholine polymers. J Biomater Sci Polym Ed. 1999;10(10):1047-61. [Content Brief]
- [2]. Yumoto H, et al. Anti-inflammatory and protective effects of 2-methacryloyloxyethyl phosphorylcholine polymer on oral epithelial cells. J Biomed Mater Res A. 2015 Feb;103(2):555-63. [Content Brief]
- [3]. Jang K, et al. An efficient surface modification using 2-methacryloyloxyethyl phosphorylcholine to control cell attachment via photochemical reaction in a microchannel. Lab Chip. 2010 Aug 7;10(15):1937-45. [Content Brief]
- [4]. Kaneko T, et al. 2-Methacryloyloxyethyl Phosphorylcholine Polymer Coating Inhibits Bacterial Adhesion and Biofilm Formation on a Suture: An In Vitro and In Vivo Study. Biomed Res Int. 2020 Oct 1;2020:5639651. [Content Brief]
