68200-68-0
Chemical Structure
5′-Deoxy-5′-iodoguanosine
Synonym(s): 5'-Iodo-5'-deoxyguanosine
- CAS No.: 68200-68-0
- Formula:C11H15N5O4
- Molecular Weight:393.14
IUPAC Name: 2-amino-9-((2R,3R,4S,5S)-3,4-dihydroxy-5-(iodomethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one
InChIKey: MELBRHQFQZYVJM-UUOKFMHZSA-N
SMILES: O=C1C2=C(NC(N)=N1)N([C@@H]3O[C@@H]([C@H]([C@H]3O)O)CI)C=N2
Biological Activity: 5'-Deoxy-5'-iodoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5′-Deoxy-5′-iodoguanosine | 5'-Deoxy-5'-iodoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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