6920-38-3
6920-38-3
Chemical Structure
Luteolin-4'-O-glucoside
- CAS 番号: 6920-38-3
- Formula:C21H20O11
- Molecular Weight:448.38
IUPAC Name: 5,7-dihydroxy-2-(3-hydroxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-4H-chromen-4-one
InChIKey: UHNXUSWGOJMEFO-QNDFHXLGSA-N
SMILES: O=C1C(C(OC(C(C=C2)=CC(O)=C2O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]([C@H]3O)CO)=C1)=CC(O)=C4)=C4O
Biological Activity: Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3].
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Luteolin-4'-O-glucoside | 99.36% | Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity. | ||||||||||||||||||||
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Luteolin-4'-O-glucoside (Standard) | ≥98% | Luteolin-4'-O-glucoside (Standard) is the analytical standard of Luteolin-4'-O-glucoside. This product is intended for research and analytical applications. Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.86
HY-N2008Luteolin 5-O-glucoside -
Similarity Score 0.86
HY-N17674Luteolin 4'-O-β-D-glucuronopyranoside -
Similarity Score 0.85
HY-N0713Diosmetin-7-O-β-D-glucopyranoside -
Similarity Score 0.85
HY-N0540RCynaroside (Standard) -
Similarity Score 0.83
HY-N10669Apigenin 4′-O-β-D-glucopyranoside -
Similarity Score 0.83
HY-N8253RSpiraeoside (Standard) -
Similarity Score 0.83
HY-N9872Quercetin 4′-O-D-galactoside -
Similarity Score 0.82
HY-1295296-Hydroxyluteolin 7-glucoside -
Similarity Score 0.81
HY-N6023Thermopsoside -
Explore the MedChemAI to find more analogs
References
- [1]. Park KY, et al. Inhibitory effect of luteolin 4'-O-glucoside from Kummerowia striata and other flavonoids on interleukin-5 bioactivity. Planta Med. 1999 Jun;65(5):457-9. [Content Brief]
- [2]. Lin Y, et al. Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models. Phytomedicine. 2018 Mar 1;41:54-61. [Content Brief]
- [3]. Xu T, et al. Glycosylation of luteolin in hydrophilic organic solvents and structure–antioxidant relationships of luteolin glycosides. RSC Advances, 2022, 12(28): 18232-18237.
