69542-93-4
69542-93-4
Chemical Structure
Pivagabine
Synonym(s): CXB-722
- CAS No.: 69542-93-4
- Formula:C9H17NO3
- Molecular Weight:187.24
IUPAC Name: 4-pivalamidobutanoic acid
InChIKey: SRPNQDXRVRCTNK-UHFFFAOYSA-N
SMILES: O=C(O)CCCNC(C(C)(C)C)=O
Biological Activity: Pivagabine (CXB 722) is a hydrophobic 4-aminobutyric acid derivative with neuromodulatory activity. Pivagabine penetrates the blood-brain barrier in rats. Pivagabine antagonizes the effects of foot shock on both GABAA receptor function and corticotropin-releasing factor (CRF) concentrations in rat brain[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pivagabine | 98.0% | Pivagabine (CXB 722) is a hydrophobic 4-aminobutyric acid derivative with neuromodulatory activity. Pivagabine penetrates the blood-brain barrier in rats. Pivagabine antagonizes the effects of foot shock on both GABAA receptor function and corticotropin-releasing factor (CRF) concentrations in rat brain. | ||||||||||||||||||||
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References
- [1]. Esposito G, et al. Pivagabine: a novel psychoactive drug. Arzneimittelforschung. 1997 Nov;47(11A):1306-9. [Content Brief]
- [2]. Serra M, et al. Antagonism by pivagabine of stress-induced changes in GABAA receptor function and corticotropin-releasing factor concentrations in rat brain. Psychoneuroendocrinology. 1999 Apr;24(3):269-84. [Content Brief]
Keywords
