69768-97-4
Chemical Structure
(E)-4-(3,4-Dimethoxyphenyl)but-3-en-1-ol
Synonym(s): DMPB
- CAS No.: 69768-97-4
- Formula:C12H16O3
- Molecular Weight:208.25
IUPAC Name: (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol
InChIKey: HJXARZMWFOEQTO-HWKANZROSA-N
SMILES: OCC/C=C/C1=CC=C(OC)C(OC)=C1
Biological Activity: (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol (DMPB) is a melanogenesis inducer. (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol increases the phosphorylation and activation of ERK and p38 MAPK. (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol increases USF1 protein levels and nuclear localization. (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol increases tyrosinase expression at both the protein and mRNA levels. (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol induces hyperpigmentation in brown guinea pigs, accompanied by increased melanin in the basal layer of the epidermis. (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol can be used for research on hypopigmentation-related diseases[1][2].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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(E)-4-(3,4-Dimethoxyphenyl)but-3-en-1-ol | 90% | (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol (DMPB) is a melanogenesis inducer. (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol increases the phosphorylation and activation of ERK and p38 MAPK. (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol increases USF1 protein levels and nuclear localization. (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol increases tyrosinase expression at both the protein and mRNA levels. (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol induces hyperpigmentation in brown guinea pigs, accompanied by increased melanin in the basal layer of the epidermis. (E)-4-(3,4-Dimethoxyphenyl) but-3-en-1-ol can be used for research on hypopigmentation-related diseases. | ||||||||||||||||||||
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References
- [1]. Amatayakul T, et al. (1979) Chemistry and Crystal Structures of Some Constituents of Zingiber cassumunar. Australian Journal of Chemistry 32, 71–88.
- [2]. Park J, et al. (E)-4-(3,4-Dimethoxyphenyl)but-3-en-1-ol Enhances Melanogenesis through Increasing Upstream Stimulating Factor-1-Mediated Tyrosinase Expression. PloS one. 2015;10(11):e0141988. [Content Brief]
