70457-70-4
70457-70-4
Chemical Structure
CGP-6809
- CAS No.: 70457-70-4
- Formula:C12H23N3O7
- Molecular Weight:321.33
IUPAC Name: 3-((R)-2-((2R,3R,4R,5S)-5-ethoxy-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-2-methoxyethyl)-1-methyl-1-nitrosourea
InChIKey: DRYAELVKAAODIB-ILAIQSSSSA-N
SMILES: O=NN(C)C(NC[C@H]([C@]1([H])[C@@H]([C@H]([C@H](O1)OCC)O)OC)OC)=O
Biological Activity: CGP-6809 is an orally active DNA inhibitor. CGP-6809 exhibits antitumor activity against various transplantable tumors in mice and rats, including melanoma, prostate cancer, and rectal cancer. CGP-6809 can be used in research on various cancers, including melanoma, prostate cancer, and rectal cancer[1][2].
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CGP-6809 | CGP-6809 is an orally active DNA inhibitor. CGP-6809 exhibits antitumor activity against various transplantable tumors in mice and rats, including melanoma, prostate cancer, and rectal cancer. CGP-6809 can be used in research on various cancers, including melanoma, prostate cancer, and rectal cancer. | |||||||||||||||||||||
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References
- [1]. Schieweck K, et al. CGP 6809, a sugar-containing nitrosourea derivative: pharmacological and physicochemical properties. Cancer Chemother Pharmacol. 1989;23(6):341-7. [Content Brief]
- [2]. Fiebig HH, et al. CGP 6809--a new nitrosoureido-sugar derivative with activity in human tumor xenografts. Cancer Chemother Pharmacol. 1989;23(6):337-40. [Content Brief]
