708291-86-5
708291-86-5
Chemical Structure
M17-B15
- CAS No.: 708291-86-5
- Formula:C18H14F3N3O3S
- Molecular Weight:409.38
InChIKey: VTTBPXATVITFMS-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)OC(C2=CC(C(F)(F)F)=CC=C2)=C1)NC3=NC(CC(C)=O)=NS3
Biological Activity: M17-B15 is an androgen receptor dimerization inhibitor with an IC50 of 30 nM. M17-B15 effectively disrupts AR self-association, thereby suppressing AR signaling. M17-B15 exhibits extraordinary anti- prostate cancer (PCa) efficacy in vitro and in mouse xenograft tumor models.M17-B15 can be used for the study of prostate cancer[1].
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M17-B15 | M17-B15 is an androgen receptor dimerization inhibitor with an IC50 of 30 nM. M17-B15 effectively disrupts AR self-association, thereby suppressing AR signaling. M17-B15 exhibits extraordinary anti- prostate cancer (PCa) efficacy in vitro and in mouse xenograft tumor models.M17-B15 can be used for the study of prostate cancer. | |||||||||||||||||||||
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References
Keywords
