72364-91-1
Chemical Structure
BRL 22321 free base
- CAS No.: 72364-91-1
- Formula:C12H9N3O2
- Molecular Weight:227.22
IUPAC Name: 6,7-dimethyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione
InChIKey: ACMSQMLLTIBBEG-UHFFFAOYSA-N
SMILES: O=C(C1=C(C2=O)C=C(C(C)=C1)C)C3=C2NN=N3
Biological Activity: BRL 22321 free base is a stabilizer with similar mast cell stabilizing activity to Cromolyn sodium (HY-B0320A) and also has some smooth muscle relaxant activity. BRL 22321 free base is more potent than Cromolyn sodium (HY-B0320A) in inhibiting rat passive cutaneous and peritoneal anaphylaxis and antigen-induced histamine release from passively sensitized rat peritoneal cells[1].
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BRL 22321 free base | BRL 22321 free base is a stabilizer with similar mast cell stabilizing activity to Cromolyn sodium (HY-B0320A) and also has some smooth muscle relaxant activity. BRL 22321 free base is more potent than Cromolyn sodium (HY-B0320A) in inhibiting rat passive cutaneous and peritoneal anaphylaxis and antigen-induced histamine release from passively sensitized rat peritoneal cells. | |||||||||||||||||||||
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