72822-12-9
72822-12-9
Chemical Structure
Dapiprazole
- CAS No.: 72822-12-9
- Formula:C19H27N5
- Molecular Weight:325.45
IUPAC Name: 3-(2-(4-(o-tolyl)piperazin-1-yl)ethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine
InChIKey: RFWZESUMWJKKRN-UHFFFAOYSA-N
SMILES: CC1=CC=CC=C1N2CCN(CCC3=NN=C4CCCCN43)CC2
Biological Activity: Dapiprazole is a potent, selective and orally active alpha-1 adrenoceptor antagonist. Dapiprazole suppresses the opioid withdrawal symptoms. Dapiprazole is also used as eye drops for reversing mydriasis[1][2][3].
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Dapiprazole | Dapiprazole is a potent, selective and orally active alpha-1 adrenoceptor antagonist. Dapiprazole suppresses the opioid withdrawal symptoms. Dapiprazole is also used as eye drops for reversing mydriasis. | |||||||||||||||||||||
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References
- [1]. Valeri P, et al. Effects of dapiprazole, clonidine and yohimbine on the development of dependence and withdrawal behaviour in mice. Drug Alcohol Depend. 1989 Jan;23(1):73-7. [Content Brief]
- [2]. Allinson RW, et al. Reversal of mydriasis by dapiprazole. Ann Ophthalmol. 1990 Apr;22(4):131-3, 138. [Content Brief]
- [3]. Hou RH, et al. Arousal and the pupil: why diazepam-induced sedation is not accompanied by miosis. Psychopharmacology (Berl). 2007 Nov;195(1):41-59. [Content Brief]
