735-16-0
735-16-0
Chemical Structure
GLUT-1-IN-4
- CAS No.: 735-16-0
- Formula:C15H10N2O3
- Molecular Weight:266.25
InChIKey: PJOXAWCIGXMTTB-AATRIKPKSA-N
SMILES: O=[N+]([O-])C1=CC=C(/C=C/C2=CC=NC3=CC=CC=C32)O1
Biological Activity: GLUT-1-IN-4 (Compound 13) is the p53 protein-dependent inhibitor for GLUT-1 glucose transporter. GLUT-1-IN-4 inhibits the proliferation of multiple cancer cells with IC50 in submicromolar levels. GLUT-1-IN-4 arrests the cell cycle, stimulates oxidative stress, and induces apoptosis[1].
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GLUT-1-IN-4 | GLUT-1-IN-4 (Compound 13) is the p53 protein-dependent inhibitor for GLUT-1 glucose transporter. GLUT-1-IN-4 inhibits the proliferation of multiple cancer cells with IC50 in submicromolar levels. GLUT-1-IN-4 arrests the cell cycle, stimulates oxidative stress, and induces apoptosis. | |||||||||||||||||||||
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