73550-55-7
73550-55-7
Chemical Structure
cis-ACBD
Synonym(s): cis-1-Aminocyclobutane-1,3-dicarboxylic acid
- CAS No.: 73550-55-7
- Formula:C6H9NO4
- Molecular Weight:159.14
IUPAC Name: (1s,3s)-1-aminocyclobutane-1,3-dicarboxylic acid
InChIKey: GGMYWPBNZXRMME-MYNUVTBMSA-N
SMILES: OC([C@]1(C[C@@H](C1)C(O)=O)N)=O
Biological Activity: cis-ACBD is a potent and selective inhibitor of the high-affinity, Na+-dependent plasma membrane glutamate transporter. cis-ACBD is a glutamate reuptake inhibitor. cis-ACBD also acts as linear competitive inhibitor of the uptake of D-[3H]aspartate[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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cis-ACBD | 98.0% | cis-ACBD is a potent and selective inhibitor of the high-affinity, Na+-dependent plasma membrane glutamate transporter. cis-ACBD is a glutamate reuptake inhibitor. cis-ACBD also acts as linear competitive inhibitor of the uptake of D-[3H]aspartate. | ||||||||||||||||||||
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References
- [1]. Ai J, et al. Presynaptic excitability as a potential target for the treatment of the traumatic cerebellum. Pharmacology. 2004 Aug;71(4):192-8. [Content Brief]
- [2]. Griffiths R, et al. L-trans-pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1,3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters. Biochem Pharmacol. 1994 Jan 20;47(2):267-74. [Content Brief]
