7423-96-3
7423-96-3
Chemical Structure
3-Fluoro-L-tyrosine
- CAS No.: 7423-96-3
- Formula:C9H10FNO3
- Molecular Weight:199.18
IUPAC Name: (S)-2-amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid
InChIKey: VIIAUOZUUGXERI-ZETCQYMHSA-N
SMILES: C1=CC(=C(C=C1C[C@@H](C(=O)O)N)F)O
Biological Activity: 3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT). And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association[1][2].
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3-Fluoro-L-tyrosine | 99.89% | 3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT). And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association. | ||||||||||||||||||||
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References
- [1]. Iron A, et al. Action of the phosphonic analogue of tyrosine and of other tyrosine derivatives on rat liver tyrosine aminotransferase. Amino Acids. 1993 Feb;5(1):33-7. [Content Brief]
- [2]. Phillips RS, et al. Effects of tyrosine ring fluorination on rates and equilibria of formation of intermediates in the reactions of carbon-carbon lyases. Eur J Biochem. 1997 Mar 1;244(2):658-63. [Content Brief]
