74447-88-4
Chemical Structure
PQQ-trimethylester
Synonym(s): PQQ-TME
- CAS. Nr.: 74447-88-4
- Formula:C17H12N2O8
- Molecular Weight:372.29
InChIKey: IYEWQFSKJDXIPI-UHFFFAOYSA-N
SMILES: O=C(C(N=C1C2=O)=CC(C(OC)=O)=C1C3=C(C=C(C(OC)=O)N3)C2=O)OC
Biological Activity: PQQ-trimethylester (PQQ-TME) is a synthetic compound that is a trimethylester derivative of pyrroloquinoline quinone (PQQ). PQQ-trimethylester has twice the blood-brain barrier permeability of PQQ (HY-100196) in vitro. In addition, PQQ-trimethylester shows strong inhibitory activity against α-synuclein, amyloid β1-42 (Aβ1-42) and prion protein fibrillation. PQQ-trimethylester can be used in the study of neurodegenerative diseases[1].
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PQQ-trimethylester | 95.0% | PQQ-trimethylester (PQQ-TME) is a synthetic compound that is a trimethylester derivative of pyrroloquinoline quinone (PQQ). PQQ-trimethylester has twice the blood-brain barrier permeability of PQQ (HY-100196) in vitro. In addition, PQQ-trimethylester shows strong inhibitory activity against α-synuclein, amyloid β1-42 (Aβ1-42) and prion protein fibrillation. PQQ-trimethylester can be used in the study of neurodegenerative diseases. | ||||||||||||||||||||
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Keywords
