745-64-2
Chemical Structure
Prostaglandin F3α
Synonym(s): PGF3α
- CAS No.: 745-64-2
- Formula:C20H32O5
- Molecular Weight:352.47
IUPAC Name: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,1E,5Z)-3-hydroxyocta-1,5-dien-1-yl)cyclopentyl)hept-5-enoic acid
InChIKey: SAKGBZWJAIABSY-SAMSIYEGSA-N
SMILES: OC(CCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)C/C=C\CC)=O
Biological Activity: Prostaglandin F3α (PGF3α) is an eicosapentaenoic acid (EPA)-derived bioactive lipid mediator that has anti-cancer and anti-inflammatory effects. Prostaglandin F3α is a substrate of ABCC4 with a Km of 12.1 μM. Prostaglandin F3α can be used for the research of diabetes[1][2].
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Prostaglandin F3α | Prostaglandin F3α (PGF3α) is an eicosapentaenoic acid (EPA)-derived bioactive lipid mediator that has anti-cancer and anti-inflammatory effects. Prostaglandin F3α is a substrate of ABCC4 with a Km of 12.1 μM. Prostaglandin F3α can be used for the research of diabetes. | |||||||||||||||||||||
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- [1]. Tanaka N, et al. Transport of eicosapentaenoic acid-derived PGE₃, PGF(3α), and TXB₃ by ABCC4. PLoS One. 2014 Oct 2;9(10):e109270. [Content Brief]
- [2]. Sailaja Devi MM, et al. Effect of prostaglandins against alloxan-induced diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids. 2006 Jan;74(1):39-60. [Content Brief]
Keywords
