752216-12-9
Chemical Structure
EBOV-IN-11
- CAS No.: 752216-12-9
- Formula:C26H25N3O6
- Molecular Weight:475.50
IUPAC Name: 1-oxo-1-ureidopropan-2-yl (E)-3-(3,4-dimethoxybenzylidene)-2,3-dihydro-1H-cyclopenta[b]quinoline-9-carboxylate
InChIKey: VAYKCOLUSSILBE-FOWTUZBSSA-N
SMILES: O=C(OC(C(=O)NC(=O)N)C)C=1C=2C=CC=CC2N=C3C(=CC4=CC=C(OC)C(OC)=C4)CCC31
Biological Activity: EBOV-IN-11 is a protein phosphatase 1 (PP1) inhibitor, with Kd values of 1.88 nM and 8.01 nM against wild-type and quadruple-mutant PP1, respectively. EBOV-IN-11 potently inhibits the replication and transcription of EBOV-eGFP virus. EBOV-IN-11 can be used in studies related to Ebola virus infection[1].
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EBOV-IN-11 | EBOV-IN-11 is a protein phosphatase 1 (PP1) inhibitor, with Kd values of 1.88 nM and 8.01 nM against wild-type and quadruple-mutant PP1, respectively. EBOV-IN-11 potently inhibits the replication and transcription of EBOV-eGFP virus. EBOV-IN-11 can be used in studies related to Ebola virus infection. | |||||||||||||||||||||
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Keywords
