75644-90-5
75644-90-5
Chemical Structure
DSLET
Synonym(s): [D-Ser2, Leu5, Thr6]-enkephalin
- CAS No.: 75644-90-5
- Formula:C33H46N6O10
- Molecular Weight:686.75
IUPAC Name: L-tyrosyl-D-serylglycyl-L-phenylalanyl-L-leucyl-L-threonine
InChIKey: PKSODCLCMBUCPW-LVNBQDLPSA-N
SMILES: C[C@@H](O)[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@@H](NC(CNC([C@@H](CO)NC([C@@H](N)CC1=CC=C(O)C=C1)=O)=O)=O)CC2=CC=CC=C2)=O)=O
Biological Activity: DSLET ([D-Ser2, Leu5, Thr6]-enkephalin) is a highly specific agonist of the δ-receptor. DSLET is an enkephalin-related peptide selectively bound to the δ opioid receptor[1][2].
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DSLET | DSLET ([D-Ser2, Leu5, Thr6]-enkephalin) is a highly specific agonist of the δ-receptor. DSLET is an enkephalin-related peptide selectively bound to the δ opioid receptor. | |||||||||||||||||||||
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References
- [1]. J L Nano, et al. Characterization of delta-opioid receptors and effect of enkephalins on IRD 98 rat epithelial intestinal cell line. Pflugers Arch. 2000 Mar;439(5):547-54. [Content Brief]
- [2]. C S Goodchild, et al. Antinociception by intrathecal midazolam involves endogenous neurotransmitters acting at spinal cord delta opioid receptors. Br J Anaesth. 1996 Dec;77(6):758-63. [Content Brief]
