75911-33-0
Chemical Structure
Taraxinic acid
- CAS No.: 75911-33-0
- Formula:C15H18O4
- Molecular Weight:262.30
InChIKey: KZWCOWFKXMTBRH-ZWXOUNMOSA-N
SMILES: O=C(/C1=C\CC/C(C)=C/[C@@]([C@](CC1)([H])C2=C)([H])OC2=O)O
Biological Activity: Taraxinic acid can be found in the roots of Taraxacum flavostylum and Taraxacum lucidum. It is a Tyrosinase inhibitor that dose-dependently inhibits Tyrosinase activity, showing approximately 54.5% inhibition at a concentration of 50 μg/mL. Taraxinic acid has an IC50 of 83.2 μM against melanoma cells A375 and HTB140, and an IC50 of 60.4 μM against melanoma cells WM793, with activity being both dose- and time-dependent. Taraxinic acid holds promise for research in the field of anticancer therapy[1].
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Taraxinic acid | Taraxinic acid can be found in the roots of Taraxacum flavostylum and Taraxacum lucidum. It is a Tyrosinase inhibitor that dose-dependently inhibits Tyrosinase activity, showing approximately 54.5% inhibition at a concentration of 50 μg/mL. Taraxinic acid has an IC50 of 83.2 μM against melanoma cells A375 and HTB140, and an IC50 of 60.4 μM against melanoma cells WM793, with activity being both dose- and time-dependent. Taraxinic acid holds promise for research in the field of anticancer therapy. | |||||||||||||||||||||
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Keywords
