7672-27-7
7672-27-7
Chemical Structure
L-NABE
- CAS No.: 7672-27-7
- Formula:C13H19N5O4
- Molecular Weight:309.32
IUPAC Name: benzyl Nw-nitro-L-argininate
InChIKey: FAJFGLZHUIUNSS-NSHDSACASA-N
SMILES: N[C@@H](CCCNC(N[N+]([O-])=O)=N)C(OCC1=CC=CC=C1)=O
Biological Activity: L-NABE is a nitric oxide (NO) synthase inhibitor. L-NABE is also a potent endothelium dependent vasoconstrictor and inhibitor of relaxation[1][2].
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L-NABE | L-NABE is a nitric oxide (NO) synthase inhibitor. L-NABE is also a potent endothelium dependent vasoconstrictor and inhibitor of relaxation. | |||||||||||||||||||||
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References
- [1]. Nossaman BD, et al. Nomega-Nitro-L-Arginine Benzyl Ester Enhances Pulmonary Vasopressor Responses to Hypoxia and to Angiotensin II. Am J Ther. 1995 Jul;2(7):462-468. [Content Brief]
- [2]. G Thomas, et al. NW-nitro L-arginine benzyl ester, a potent irreversible inhibitor of endothelium dependent relaxation. Biochem Biophys Res Commun. 1991 Sep 30;179(3):1677-82. [Content Brief]
