769872-68-6
Chemical Structure
8-Chloro-arabinoadenosine
- CAS No.: 769872-68-6
- Formula:C10H12ClN5O4
- Molecular Weight:301.69
IUPAC Name: (2R,3S,4S,5R)-2-(6-amino-8-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
InChIKey: MHDPPLULTMGBSI-FJFJXFQQSA-N
SMILES: O[C@H]1[C@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2Cl)O[C@@H]1CO
Biological Activity: 8-Chloro-arabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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8-Chloro-arabinoadenosine | 8-Chloro-arabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords