77263-11-7
Chemical Structure
Abyssinone V
- CAS No.: 77263-11-7
- Formula:C25H28O5
- Molecular Weight:408.49
IUPAC Name: (S)-5,7-dihydroxy-2-(4-hydroxy-3,5-bis(3-methylbut-2-en-1-yl)phenyl)chroman-4-one
InChIKey: LQHKFMYWTKORCE-QFIPXVFZSA-N
SMILES: O=C1C(C(O[C@H](C(C=C2C/C=C(C)/C)=CC(C/C=C(C)/C)=C2O)C1)=CC(O)=C3)=C3O
Biological Activity: Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V can be isolated from the stem bark of Erythrina melanacantha. Abyssinone V possesses good pharmacodynamics properties. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity[1][2].
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Abyssinone V | Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V can be isolated from the stem bark of Erythrina melanacantha. Abyssinone V possesses good pharmacodynamics properties. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity. | |||||||||||||||||||||
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References
- [1]. Koch K, et al. Abyssinone V, a prenylated flavonoid isolated from the stem bark of Erythrina melanacantha increases oxidative stress and decreases stress resistance in Caenorhabditis elegans. J Pharm Pharmacol. 2019 Jun;71(6):1007-1016. [Content Brief]
- [2]. Kwofie SK, et al. Identification of novel potential inhibitors of varicella-zoster virus thymidine kinase from ethnopharmacologic relevant plants through an in-silico approach. J Biomol Struct Dyn. 2022;40(23):12932-12947. [Content Brief]
