7758-73-8
7758-73-8
Chemical Structure
LC3-mHTT-IN-AN2
- CAS No.: 7758-73-8
- Formula:C15H10O4
- Molecular Weight:254.24
IUPAC Name: 5,7-dihydroxy-4-phenyl-2H-chromen-2-one
InChIKey: HUQKUJNSVHEHIH-UHFFFAOYSA-N
SMILES: OC1=C2C(OC(C=C2C3=CC=CC=C3)=O)=CC(O)=C1
Biological Activity: LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LC3-mHTT-IN-AN2 | 99.09% | LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.84
HY-N4287Nordalbergin -
Similarity Score 0.81
HY-W2071957-Hydroxy-4-phenylcoumarin -
Similarity Score 0.79
HY-14589Chrysin -
Similarity Score 0.78
HY-N8347Dalbergin -
Similarity Score 0.78
HY-1284104-Phenyl-7,8-dihydroxycoumarin -
Similarity Score 0.74
HY-124184D715-2441 -
Similarity Score 0.73
HY-N0382RGalangin (Standard) -
Similarity Score 0.73
HY-N0382SGalangin-13C3 -
Similarity Score 0.70
HY-156360Xanthine oxidase-IN-12 -
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