7758-73-8

LC3-mHTT-IN-AN2 Chemical Structure
7758-73-8

Chemical Structure

LC3-mHTT-IN-AN2

  • CAS No.: 7758-73-8
  • Formula:C15H10O4
  • Molecular Weight:254.24

IUPAC Name: 5,7-dihydroxy-4-phenyl-2H-chromen-2-one

InChIKey: HUQKUJNSVHEHIH-UHFFFAOYSA-N

SMILES: OC1=C2C(OC(C=C2C3=CC=CC=C3)=O)=CC(O)=C1

Biological Activity: LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].

Cat. No. Product Name Purity Description Pricing
HY-130259
LC3-mHTT-IN-AN2 98.87% LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References