79355-89-8
Chemical Structure
Bartogenic acid
- CAS No.: 79355-89-8
- Formula:C30H46O7
- Molecular Weight:518.68
InChIKey: BBJQJXRZAZWPBL-AOVBODNOSA-N
SMILES: OC([C@]12[C@]([C@@H](C(C)(CC2)C)O)([H])C3=CC[C@@]([C@@]4([C@@]([C@](C)([C@H]([C@@H](C4)O)O)C(O)=O)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
Biological Activity: Bartogenic acid is an orally active NF-κB inhibitor, found in Barringtonia racemosa fruits. Bartogenic acid increases catalase, superoxide dismutase (SOD), and glutathione levels. Bartogenic acid inhibits lipid peroxidation and suppresses inflammation markers. Bartogenic acid can be used for the research of ovarian cancer, skin cancer, and inflammatory conditions[1][2][3][4].
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Bartogenic acid | Bartogenic acid is an orally active NF-κB inhibitor, found in Barringtonia racemosa fruits. Bartogenic acid increases catalase, superoxide dismutase (SOD), and glutathione levels. Bartogenic acid inhibits lipid peroxidation and suppresses inflammation markers. Bartogenic acid can be used for the research of ovarian cancer, skin cancer, and inflammatory conditions. | |||||||||||||||||||||
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- [1]. Dubey VK, et al. Tumor-suppressing effect of bartogenic acid in ovarian (SKOV-3) xenograft mouse model. Naunyn Schmiedebergs Arch Pharmacol. 2021;394(8):1815-1826. [Content Brief]
- [2]. Patil CR, et al. Chemomodulatory Potential of Bartogenic Acid Against DMBA/Croton Oil Induced Two-Step Skin Carcinogenesis in Mice. J Cancer. 2016;7(14):2139-2147. Published 2016 Oct 23. [Content Brief]
- [3]. Patil KR, et al. Anti-Arthritic Activity of Bartogenic Acid Isolated from Fruits of Barringtonia racemosa Roxb. (Lecythidaceae). Evid Based Complement Alternat Med. 2011;2011:785245. [Content Brief]
- [4]. Patil KR, et al. Anti-inflammatory activity of bartogenic acid containing fraction of fruits of Barringtonia racemosa Roxb. in acute and chronic animal models of inflammation. J Tradit Complement Med. 2016 Apr 4;7(1):86-93. [Content Brief]
Keywords
