80263-73-6
80263-73-6
Chemical Structure
REV 2871
Synonym(s): Eclazolast; CHBZ
- CAS. Nr.: 80263-73-6
- Formula:C12H12ClNO4
- Molecular Weight:269.68
IUPAC Name: 2-ethoxyethyl 5-chlorobenzo[d]oxazole-2-carboxylate
InChIKey: HNJUBRBHULQQFX-UHFFFAOYSA-N
SMILES: CCOCCOC(C1=NC(C=C(Cl)C=C2)=C2O1)=O
Biological Activity: REV 2871 (Eclazolast; CHBZ) is a potent and oral activity antiallergic agent. REV 2871 also is an irreversibility histamine release (HR) inhibitor[1][2].
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REV 2871 | REV 2871 (Eclazolast; CHBZ) is a potent and oral activity antiallergic agent. REV 2871 also is an irreversibility histamine release (HR) inhibitor. | |||||||||||||||||||||
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References
- [1]. Coutts SM, et al. REV 2871 (CHBZ): a potent antiallergic agent with a novel mechanism of action. II. Studies on the mechanism of action. Biochem Pharmacol. 1987 Mar 1;36(5):673-82. [Content Brief]
- [2]. Khandwala A, et al. REV 2871 (CHBZ): a potent antiallergic agent with a novel mechanism of action. I. Activity profile as an inhibitor of mediator release. Biochem Pharmacol. 1987 Mar 1;36(5):663-72. [Content Brief]
