80274-67-5
80274-67-5
Chemical Structure
Metoprolol fumarate
Synonym(s): CGP 2175C; Lopressor OROS
- CAS No.: 80274-67-5
- Formula:C34H54N2O10
- Molecular Weight:650.80
IUPAC Name: 1-(isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol hemifumarate
InChIKey: BRIPGNJWPCKDQZ-WXXKFALUSA-N
SMILES: OC(CNC(C)C)COC1=CC=C(CCOC)C=C1.O=C(O)/C=C/C(O)=O.OC(CNC(C)C)COC2=CC=C(CCOC)C=C2
Biological Activity: Metoprolol fumarate (CGP 2175C) is an orally active, selective β1-adrenoceptor antagonist. Metoprolol fumarate shows anti-inflammation, antitumor and anti-angiogenic properties[1][2][3].
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Metoprolol fumarate | Metoprolol fumarate (CGP 2175C) is an orally active, selective β1-adrenoceptor antagonist. Metoprolol fumarate shows anti-inflammation, antitumor and anti-angiogenic properties. | |||||||||||||||||||||
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References
- [1]. Ulleryd MA, et al. Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. Biomed Res Int. 2014;2014:548783. [Content Brief]
- [2]. Wang D, et al. Carvedilol has stronger anti-inflammation and anti-virus effects than metoprolol in murine model with coxsackievirus B3-induced viral myocarditis. Gene. 2014 Sep 1;547(2):195-201. [Content Brief]
- [3]. Hajatbeigi B, et al. Cytotoxicity of Metoprolol on Leukemic Cells in Vitro. IJBC 2018; 10(4): 124-129.
Keywords
