802915-53-3
802915-53-3
Chemical Structure
Fusarochromanone
Synonym(s): FC-101
- CAS No.: 802915-53-3
- Formula:C15H20N2O4
- Molecular Weight:292.33
IUPAC Name: (R)-5-amino-6-(3-amino-4-hydroxybutanoyl)-2,2-dimethylchroman-4-one
InChIKey: COSICWYFCAPPJB-MRVPVSSYSA-N
SMILES: O=C1CC(C)(C)OC2=CC=C(C(C[C@@H](N)CO)=O)C(N)=C12
Biological Activity: Fusarochromanone (FC-101) is a fungal metabolite with potent anti-angiogenic and anti-cancer activity[1]. Fusarochromanone-activated JNK pathway is attributed to induction of reactive oxygen species (ROS)[2].
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Fusarochromanone | Fusarochromanone (FC-101) is a fungal metabolite with potent anti-angiogenic and anti-cancer activity. Fusarochromanone-activated JNK pathway is attributed to induction of reactive oxygen species (ROS). | |||||||||||||||||||||
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References
- [1]. Elahe Mahdavian, et al.Biological activities of fusarochromanone: a potent anti-cancer agent. BMC Res Notes. 2014 Sep 3;7:601. [Content Brief]
- [2]. Ying Gu, et al.Fusarochromanone-induced reactive oxygen species results in activation of JNK cascade and cell death by inhibiting protein phosphatases 2A and 5. Oncotarget. 2015 Dec 8;6(39):42322-33. [Content Brief]
Keywords
