80508-42-5
80508-42-5
Chemical Structure
Tenacigenin B
- CAS No.: 80508-42-5
- Formula:C21H32O5
- Molecular Weight:364.48
IUPAC Name: 1-((1R,3aR,4aS,6aS,8S,10aS,10bS,11S,12S,12aS)-8,11,12-trihydroxy-10a,12a-dimethyltetradecahydro-1H-cyclopenta[1,2]phenanthro[1,10a-b]oxiren-1-yl)ethanone
InChIKey: FWXVLSDGEDMLQU-APDNMBNPSA-N
SMILES: C[C@@]12[C@]3(CC[C@H]2C(C)=O)[C@]4([C@@]([C@@H]([C@H]1O)O)([H])[C@@]5([C@@](C[C@H](CC5)O)([H])CC4)C)O3
Biological Activity: Tenacigenin B is a steroid that can be isolated from the genus Alocasia. Tenacigenin B has anti-tumor effects on lymphoma via regulation of Aurora-A[1][2].
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Tenacigenin B | Tenacigenin B is a steroid that can be isolated from the genus Alocasia. Tenacigenin B has anti-tumor effects on lymphoma via regulation of Aurora-A. | |||||||||||||||||||||
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References
- [1]. Peng W, et al. The cytotoxic and tyrosine kinase inhibitory properties of C21 steroids and iridoids from the tubers of Alocasia cucullata. J Nat Med. 2016 Jul;70(3):602-9. [Content Brief]
- [2]. Dai X, et al. Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study. Med Sci Monit. 2019 Sep 1;25:6563-6573. [Content Brief]
Keywords
