81246-79-9
81246-79-9
Chemical Structure
5'-O-DMT-rU
Synonym(s): 5'-O-DMT-Uridine
- CAS No.: 81246-79-9
- Formula:C30H30N2O8
- Molecular Weight:546.57
IUPAC Name: 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: PCFSNQYXXACUHM-YULOIDQLSA-N
SMILES: O[C@@H]([C@@H](O)[C@H](N1C(NC(C=C1)=O)=O)O2)[C@H]2COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5
Biological Activity: 5'-O-DMT-rU (5'-O-DMT-Uridine) is a 5'-O-dimethoxytrityl-protected uridine derivative that serves as a synthetic precursor for the preparation of bicyclic uridine derivatives with ribose 2'- and 3'-fused 18-crown-6 ether moieties[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5'-O-DMT-rU | 98.06% | 5'-O-DMT-rU (5'-O-DMT-Uridine) is a 5'-O-dimethoxytrityl-protected uridine derivative that serves as a synthetic precursor for the preparation of bicyclic uridine derivatives with ribose 2'- and 3'-fused 18-crown-6 ether moieties. | ||||||||||||||||||||
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References
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[1]. Ali Khalafi-Nezhad, et al. A catalytic method for chemoselective detritylation of 5′-tritylated nucleosides under mild and heterogeneous conditions using silica sulfuric acid as a recyclable catalyst, Tetrahedron Letters, Volume 48, Issue 30,
2007, Pages 5219-5222, ISSN 0040-4039. -
[2]. Cinzia Coppola, et al. Synthesis and NMR characterization of a novel crown-ether ring-fused uridine analogue, Tetrahedron,
Volume 66, Issue 34, 2010, Pages 6769-6774, ISSN 0040-4020. - [3]. Singh SK, et al. Selective biocatalytic acylation studies on 5'-O-(4,4'-dimethoxytrityl)-2',3'-secouridine: an efficient synthesis of UNA monomer. Nucleosides Nucleotides Nucleic Acids. 2012;31(12):831-40.
