82889-99-4
82889-99-4
Chemical Structure
(Z)-Iloprost
Synonym(s): (Z)-Ciloprost; (Z)-ZK 36374
- CAS No.: 82889-99-4
- Formula:C22H32O4
- Molecular Weight:360.49
IUPAC Name: 5-((3aS,4R,5R,6aS,Z)-5-hydroxy-4-((3S,E)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl)hexahydropentalen-2(1H)-ylidene)pentanoic acid
InChIKey: HIFJCPQKFCZDDL-UGQITTIWSA-N
SMILES: CC#CCC(C)[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@@](C[C@H]1O)([H])C/C(C2)=C/CCCC(O)=O
Biological Activity: (Z)-Iloprost ((Z)-Ciloprost; (Z)-ZK 36374) is a vasodilator that prevents heparin-induced platelet activation[1][2][3].
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(Z)-Iloprost | (Z)-Iloprost ((Z)-Ciloprost; (Z)-ZK 36374) is a vasodilator that prevents heparin-induced platelet activation. | |||||||||||||||||||||
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References
- [1]. Rücker W, et al. Evidence for high affinity prostacyclin binding sites in vascular tissue: radioligand studies with a chemically stable analogue. Biochem Pharmacol. 1983 Aug 15;32(16):2405-10. [Content Brief]
- [2]. Sharma A, et al. Role of Vasodilator Testing in Pulmonary Hypertension. Prog Cardiovasc Dis. 2016 Jan-Feb;58(4):425-33.
Keywords
