82972-54-1
82972-54-1
Chemical Structure
Diazoketone methotrexate
- CAS No.: 82972-54-1
- Formula:C21H22N10O4
- Molecular Weight:478.46
IUPAC Name: (S)-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-6-diazo-5-oxohexanoic acid
InChIKey: DUYMESGXUXXYQB-HNNXBMFYSA-N
SMILES: NC1=NC(N)=NC2=NC=C(CN(C3=CC=C(C(N[C@H](C(O)=O)CCC(C=[N+]=[N-])=O)=O)C=C3)C)N=C12
Biological Activity: Diazoketone methotrexate, an analog of methotrexate, is an antitumor agent. Diazoketone methotrexate inhibits cell growth and inhibits synthesis of thymidylate[1].
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Diazoketone methotrexate | Diazoketone methotrexate, an analog of methotrexate, is an antitumor agent. Diazoketone methotrexate inhibits cell growth and inhibits synthesis of thymidylate. | |||||||||||||||||||||
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References
Keywords
