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Cat. No.: HY-129870

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Diazoketone methotrexate

Diazoketone methotrexate, an analog of methotrexate, is an antitumor agent. Diazoketone methotrexate inhibits cell growth and inhibits synthesis of thymidylate.

For research use only. We do not sell to patients.

CAS No.: 82972-54-1
Formula: C₂₁H₂₂N₁₀O₄
Molecular Weight:478.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Diazoketone methotrexate Chemical Structure

CAS No.: 82972-54-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Diazoketone methotrexate, an analog of methotrexate, is an antitumor agent. Diazoketone methotrexate inhibits cell growth and inhibits synthesis of thymidylate^[1].

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 82972-54-1
Molecular Weight 478.46
Formula C₂₁H₂₂N₁₀O₄
SMILES

NC1=NC(N)=NC2=NC=C(CN(C3=CC=C(C(N[C@H](C(O)=O)CCC(C=[N+]=[N-])=O)=O)C=C3)C)N=C12
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gangjee A, et al. Diazoketone and chloromethylketone analogs of methotrexate as potential antitumor agents. J Pharm Sci. 1982 Jun;71(6):717-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Diazoketone methotrexate

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Diazoketone methotrexate Related Classifications

HY-129870 Related Classifications