83199-32-0
Chemical Structure
Sp-TTPαS
- CAS No.: 83199-32-0
- Formula:C10H17N2O13P3S
- Molecular Weight:498.23
InChIKey: PXHHTOSRELKWOE-ISVKTPMGSA-N
SMILES: O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1CO[P@@](OP(OP(O)(O)=O)(O)=O)(S)=O
Biological Activity: Sp-TTPαS is a competitivesterile alpha motif and HD domain containing protein 1 (SAMHD1) hydrolysis inhibitor. Sp-TTPαS competitively inhibits SAMHD1 triphosphohydrolase activity with a Ki value of 46 µM[1].
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Sp-TTPαS | Sp-TTPαS is a competitivesterile alpha motif and HD domain containing protein 1 (SAMHD1) hydrolysis inhibitor. Sp-TTPαS competitively inhibits SAMHD1 triphosphohydrolase activity with a Ki value of 46 µM. | |||||||||||||||||||||
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Keywords