833473-68-0
833473-68-0
Chemical Structure
GW837016X
Synonym(s): NEU-391
- CAS No.: 833473-68-0
- Formula:C25H20ClFN4OS
- Molecular Weight:478.97
IUPAC Name: (S)-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(pyrrolidin-2-ylethynyl)thieno[3,2-d]pyrimidin-4-amine
InChIKey: FNYHTKUCTLSINN-SFHVURJKSA-N
SMILES: FC1=CC(COC2=CC=C(NC3=C4C(C=C(C#C[C@H]5NCCC5)S4)=NC=N3)C=C2Cl)=CC=C1
Biological Activity: GW837016X (NEU-391) is an orally active ErbB-2 kinase covalent inhibitor. GW837016X also is a potent antitrypanosome agent. GW837016X inhibits mitosis and cytokinesis[1].
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GW837016X | GW837016X (NEU-391) is an orally active ErbB-2 kinase covalent inhibitor. GW837016X also is a potent antitrypanosome agent. GW837016X inhibits mitosis and cytokinesis. | |||||||||||||||||||||
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References
Keywords
