83373-60-8
83373-60-8
Chemical Structure
D609
- CAS No.: 83373-60-8
- Formula:C11H15KOS2
- Molecular Weight:266.46
IUPAC Name: potassium O-(octahydro-1H-4,7-methanoinden-5-yl) carbonodithioate
InChIKey: IGULCCCBGBDZKQ-UHFFFAOYSA-M
SMILES: S=C(OC1C2C3CCCC3C(C1)C2)S[K]
Biological Activity: D609, an antitumoural xanthate, is a specific and competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor with a Ki of 6.4 μM. D609 is an antioxidative protector and has antiviral and anti-inflammatory activity[1][2][3].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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D609 | 98.0% | D609, an antitumoural xanthate, is a specific and competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor with a Ki of 6.4 μM. D609 is an antioxidative protector and has antiviral and anti-inflammatory activity. | ||||||||||||||||||||
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References
- [1]. E Amtmann, et al. The antiviral, antitumoural xanthate D609 is a competitive inhibitor of phosphatidylcholine-specific phospholipase C. Drugs Exp Clin Res. 1996;22(6):287-94. [Content Brief]
- [2]. Gusain A, et al. Anti-proliferative effects of tricyclodecan-9-yl-xanthogenate (D609) involve ceramide and cell cycle inhibition.Mol Neurobiol. 2012 Jun;45(3):455-64. Epub 2012 Mar 14. [Content Brief]
- [3]. Lu Zhang, et al. D609 inhibits progression of preexisting atheroma and promotes lesion stability in apolipoprotein e-/- mice: a role of phosphatidylcholine-specific phospholipase in atherosclerosis. Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):411-8. [Content Brief]
Keywords
