84380-01-8
Chemical Structure
α-Arbutin
Synonym(s): 4-Hydroxyphenyl α-D-glucopyranoside
- CAS No.: 84380-01-8
- Formula:C12H16O7
- Molecular Weight:272.25
IUPAC Name: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: BJRNKVDFDLYUGJ-ZIQFBCGOSA-N
SMILES: OC(C=C1)=CC=C1O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO
Biological Activity: α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is a tyrosinase inhibitor, which is used as an effective skin whiteners. α-Arbutin is promising for research of various diseases such as hyperpigmentation disorders, types of cancers, central nervous system disorders, osteoporosis, diabetes[1][2][3][4].
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α-Arbutin | 99.97% | α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is a tyrosinase inhibitor, which is used as an effective skin whiteners. α-Arbutin is promising for research of various diseases such as hyperpigmentation disorders, types of cancers, central nervous system disorders, osteoporosis, diabetes. | ||||||||||||||||||||
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α-Arbutin (Standard) | 99.65% | α-Arbutin (Standard) is the analytical standard of α-Arbutin. This product is intended for research and analytical applications. α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is emerging as popular and effective skin whiteners, acting as tyrosinase inhibitor. | ||||||||||||||||||||
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- [1]. Avonto C, et al. Comparative studies on the chemical and enzymatic stability of alpha- and beta-arbutin.Int J Cosmet Sci. 2016 Apr;38(2):187-93. [Content Brief]
- [2]. Saeedi M, et al. A comprehensive review of the therapeutic potential of α-arbutin. Phytother Res. 2021 Aug;35(8):4136-4154. [Content Brief]
- [3]. Sugimoto K, et al. Inhibitory effects of alpha-arbutin on melanin synthesis in cultured human melanoma cells and a three-dimensional human skin model. Biol Pharm Bull. 2004 Apr;27(4):510-4. [Content Brief]
- [4]. Hazman Ö, et al. Two faces of arbutin in hepatocellular carcinoma (HepG2) cells: Anticarcinogenic effect in high concentration and protective effect against cisplatin toxicity through its antioxidant and anti-inflammatory activity in low concentration[J]. Biologia, 2022, 77(1): 225-239.
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